Nithin Karakala

Professor

University of Arkansas for Medical Sciences

faculty

Internal Med, College of Medicine

13 h-index 39 pubs 644 cited

Research Areas

Dialysis and Renal Disease Management Emergency and Acute Care Studies Immune Response and Inflammation Metabolomics and Mass Spectrometry Studies Biomarkers in Renal Disease Health Sciences Research and Education Cardiovascular Function and Risk Factors

Links

ORCID Lab Website UAMS TRI Profile

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OverviewAI-generated summary

Nithin Karakala, Professor in the Department of Internal Medicine at the University of Arkansas for Medical Sciences, focuses his research on biomarkers in renal disease. His clinical interests include continuous renal replacement therapy, early prognostic markers of acute kidney injury, and volume management in acute kidney injury. Dr. Karakala received his medical degree from Deccan College of Medical Sciences in India and completed his internal medicine residency at Greater Baltimore Medical Center. He finished his nephrology fellowship training at the Medical University of South Carolina, where he also served as Chief Nephrology Fellow before joining the faculty at UAMS.

Dr. Karakala's research has been published in numerous journals, with recent work exploring urinary NGAL as a marker for acute kidney injury in cirrhosis, the role of SOD1 as a prognostic biomarker after cardiothoracic surgery, and the prognostic significance of IGFBP-1 in acute kidney injury. His collaborative network includes researchers at the University of Arkansas for Medical Sciences, such as Luis A. Juncos, Joseph H. Holthoff, Manisha Singh, and Neriman Gökden, with whom he has co-authored multiple publications. He maintains an active laboratory website to share his work. Dr. Karakala's scholarship is reflected in his h-index of 13, with 39 total publications and 644 citations.

Research Overview

Dr. Karakala is an Assistant Professor of Medicine in the Division of Nephrology, Department of Internal Medicine. He received his medical degree from Deccan College of Medical Sciences in India. He completed his internal medicine residency at Greater Baltimore Medical Center in Maryland and his nephrology fellowship training at Medical University of South Carolina. He served as the Chief Nephrology Fellow at MUSC as well. Dr. Karakala was on the faculty at MUSC for two years before coming to UAMS. Dr. Karakala is board certified in internal medicine and nephrology. His clinical interests are continuous renal replacement therapy, early prognostic markers of acute kidney injury, and volume management in acute kidney injury. His research interests include biomarkers in renal disease.

Metrics

  • h-index: 13
  • Publications: 39
  • Citations: 644

Selected Publications

  • Perfusion Under Pressure: Reversing Anuric AKI with Targeted Intra-Abdominal Pressure (IAP) Reduction (2025) DOI
  • Hypophosphatemia as a Marker for Immune Effector Cell-Associated Neurotoxicity Syndrome in Chimeric Antigen Receptor T Cell Recipients (2025) DOI
  • SGLT2 Inhibitors as a Therapeutic Option for Both Acute and Chronic Refractory Hypomagnesemia in Diabetic and Nondiabetic Patients: A Multicenter Case Series (2025) DOI
  • The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury (2025) DOI
  • Gastrointestinal Mucosal Cell Injury Caused by Sevelamer Crystals: Case Series and Literature Review (2025) DOI
  • Urine Chemistry: A Valuable Link Binding Kidney Physiology to Patient Care (2024) DOI
  • Stepwise Teamwork Approach Saves Patients Extensive Work-Up (2024) DOI
  • I Am in a Crystal Bind! A Case that Gave Us Ulcers (2023) DOI
  • The Drug that Keeps Giving: Hypomagnesemia Fixed by SGLT2 Inhibitor (2023) DOI
  • SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery (2023) DOI
  • High-Cutoff Hemodialysis Therapy for Patients with Light Chain Cast Nephropathy and AKI Requiring Dialysis: CON (2023) DOI
  • Responsiveness to Vasoconstrictor Therapy in Hepatorenal Syndrome Type 1 (2023) DOI
  • Incidence of Hypophosphatemia During Continuous Renal Replacement Therapy: Baseline Data for a Quality Improvement Initiative (2021) DOI
  • Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward (2021) DOI
  • Point-of-Care Ultrasound in Acute Care Nephrology (2021) DOI

Grants & Funding

  • Clinical Scientist Award UAMS Principal Investigator
  • No FP attached Potrero Medical - Pass Through: Biomedical Research Foundation - Arkansas Principal Investigator
  • Clinical Scientist Award UAMS Principal Investigator
  • Targeting Abdominal Perfusion Pressure in Septic Shock (The MAP APP Study) IRB 228252 Potrero Medical - Pass Through: Biomedical Research Foundation - Arkansas Principal Investigator

Collaborators

Researchers in the database who share publications

Luis A. Juncos University of Arkansas for Medical Sciences 8 shared publications Joseph H. Holthoff University of Arkansas for Medical Sciences 6 shared publications Manisha Singh University of Arkansas for Medical Sciences 2 shared publications Neriman Gökden University of Arkansas for Medical Sciences 2 shared publications Christian Herzog University of Arkansas for Medical Sciences 2 shared publications Yanping Izak Harville University of Arkansas for Medical Sciences 2 shared publications Fatima Ayub University of Arkansas for Medical Sciences 2 shared publications Randall R Rainwater University of Arkansas for Medical Sciences 1 shared publication

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