Rick D. Edmondson

High Impact

Professor

University of Arkansas for Medical Sciences

faculty

Biochemistry & Molecular Biology, College of Medicine

32 h-index 90 pubs 4,439 cited

Research Areas

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OverviewAI-generated summary

Rick D. Edmondson, Professor in Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences, leads a research group focused on molecular mechanisms underlying disease, particularly cancer and bone metabolism. His work investigates how cellular processes like phase separation, iron uptake, and chromatin modification contribute to disease development and progression.

Recent publications from his group include studies on phase separation driving aberrant chromatin looping and cancer, the role of transferrin receptor 1 in regulating bone mass via osteoclast mitochondria and cytoskeleton, and the mechanism by which TNRC18 silences endogenous retrotransposons. His research also explores oncogenic mechanisms, such as how NUP98 oncofusions form condensates that partition transcriptional coactivators and how ZMYND11-MBTD1 hijacks the NuA4/TIP60 complex in leukemogenesis. Further investigations examine the conserved BAH module within BAHD1 connecting H3K27me3 to Polycomb gene silencing.

Edmondson has a distinguished publication record with 90 total publications and 4,439 citations, reflected in his h-index of 32 and designation as a highly cited researcher. He actively collaborates with colleagues at the University of Arkansas for Medical Sciences, including Samuel G. Mackintosh (12 shared publications), Alan J. Tackett (9 shared publications), Aaron J. Storey (7 shared publications), and Dr. Stephanie Byrum (6 shared publications), indicating a strong network within his institution.

Metrics

h-index: 32
Publications: 90
Citations: 4,439

Selected Publications

Multiplexed Detection of Membranous Antigens by Mass Spectrometry (2025) DOI
YY1 relieves p300 autoinhibition to promote histone acetylation in advanced prostate cancer, enhancing the oncogenic signaling of Androgen Receptor Splice Variant 7 (2025) DOI
The phenylalanine-and-glycine repeats of NUP98 oncofusions form condensates that selectively partition transcriptional coactivators (2025) DOI
TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons (2023) DOI
Proteogenomics Analysis to Identify Acquired Resistance-Specific Alterations in Melanoma PDXs on MAPKi Therapy (2023) DOI
Minor Antigens in Membranous Nephropathy Identified by Mass Spectrometry (2022) DOI
Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton (2022) DOI
Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton (2022) DOI
Proteogenomics analysis to identify acquired resistance-specific alterations in melanoma PDXs on MAPKi therapy (2022) DOI
Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton (2021) DOI
Phase separation drives aberrant chromatin looping and cancer development (2021) DOI
Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer (2021) DOI
A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing (2021) DOI
A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing (2021) DOI
ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism (2021) DOI

Grants & Funding

Identification of Druggable Targets to Complement Melanoma Therapy NIH Co-Investigator
Development of biomarkers for improved classification of proliferative lupus nephritis NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: Arkana Laboratories Co-Investigator
Role of HELB in the Replication Stress Response Dr. Tacketts COBRA through ACRI NIH/Nat. Inst. of General Medical Sciences - Pass Through: Arkansas Children's Research Institute Co-Investigator
Biomarkers of Early Renal Functional Decline in Type 2 Diabetes NIH Co-Investigator
IDeA National Resource for Quantitative Proteomics NIH Co-Investigator
Development of a Precision Medicine-Based Diagnostic Tool for Membranous Nephropathy NIH/National Institutes of Health - Pass Through: Arkana Laboratories Principal Investigator
Discovery and Characterization of Novel Sepsis Proteome Biomarkers NIH Co-Investigator