Shelby N. Bess Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Graduate Assistant

University of Arkansas at Fayetteville

faculty

5 h-index 18 pubs 53 cited

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Biography and Research Information

OverviewAI-generated summary

Shelby N. Bess's research investigates the function and metabolic activity of immune cells, particularly macrophages, in the context of cancer and inflammation. Their work utilizes advanced imaging techniques, such as autofluorescence and diffuse reflectance spectroscopy, to quantitatively assess cellular processes. Publications explore the role of specific molecules like CCL2 and CD47 in modulating the tumor microenvironment and enhancing the efficacy of cancer therapies. Bess has also studied the development of multicellular tumor spheroids and their metabolic profiles, alongside the creation of assays for screening gene delivery vehicles for macrophage applications. Collaborations include Timothy J. Muldoon, Matthew J. Igoe, Gaven K. Smart, and Christopher E. Nelson, with whom Bess has co-authored multiple publications.

Metrics

  • h-index: 5
  • Publications: 18
  • Citations: 53

Selected Publications

  • Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025) DOI
  • Quantifying treatment response to a macrophage-targeted therapy in combination with immune checkpoint inhibitors after exposure to conventional chemotherapy (2025) DOI
  • The Physiological and Therapeutic Role of CD47 in Macrophage Function and Cancer (2024) DOI
  • Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles (2024) DOI
  • Abstract 5549: Multicellular spheroid structural and metabolic characterization through radial line profiling (2024) DOI
  • Live-Cell Imaging Quantifies Changes in Function and Metabolic NADH Autofluorescence During Macrophage-Mediated Phagocytosis of Tumor Cells (2023) DOI
  • Autofluorescence imaging of endogenous metabolic cofactors in response to cytokine stimulation of classically activated macrophages (2023) DOI
  • Minimally invasive in vivo endoscopic monitoring of dextran sulfate sodium-induced murine colitis (2022) DOI
  • Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy (2022) DOI
  • Abstract P009: Correlation between immune modulation of macrophage recruitment and new blood vessel formation in a subcutaneous murine mouse model of colorectal cancer (2022) DOI

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