Yunping Guo

Researcher

University of Arkansas for Medical Sciences

faculty

3 h-index 16 pubs 64 cited

Research Areas

Blood Pressure and Hypertension Studies Immune Response and Inflammation Immune Cell Function and Interaction Cardiovascular Function and Risk Factors T-cell and B-cell Immunology Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Yunping Guo's research program investigates the intricate connections between the immune system and cardiovascular health, with a particular focus on hypertension. Guo has published work exploring how specific immune pathways, such as the IFNγ-PDL1 pathway, influence T-cell interactions with kidney cells, thereby promoting salt-sensitive hypertension. Further research examines the role of P2X7-mediated CD8+ T cell activation in this condition and the contribution of immune memory to chronic hypertension recurrence.

Additional studies delve into the immunological underpinnings of cardiac dysfunction and the transition of macrophages to myofibroblasts in the development of diastolic dysfunction. Guo also studies the role of kidney-resident memory T cells in the chronic progression of hypertension. Guo's scholarly output includes 16 publications, with a total of 64 citations and an h-index of 3. Key collaborators include Shengyu Mu, Katherine Deck, and Christoph Mora, all from the University of Arkansas for Medical Sciences, with whom Guo shares multiple publications.

Metrics

  • h-index: 3
  • Publications: 16
  • Citations: 64

Selected Publications

  • Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024) DOI
  • Abstract P335: An innate immune component in hypertension-induced cardiac dysfunction Christoph Mora, Katherine Deck, Yunmeng Liu, Lance Benson, Tonya Rafferty, & Shengyu Mu (2024) DOI
  • P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024) DOI
  • O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION (2024) DOI
  • Kidney resident memory CD8 T cells mediate recurrence of salt-sensitive hypertension (2024) DOI
  • Macrophage to Myofibroblast Transition Promotes Hypertension-Induced Cardiac Diastolic Dysfunction (2024) DOI
  • Macrophage to Myofibroblast Transition in Diastolic Dysfunction Development (2023) DOI
  • The link between immunity and hypertension in the kidney and heart (2023) DOI
  • S-40-5: ROLE OF INTERFERON GAMMA IN T CELL MEDIATED SALT-RETENTION IN THE KIDNEY AND PROGRESSION OF HYPERTENSION (2023) DOI
  • The IFNγ‐PDL1 Pathway Enhances the Interaction Between CD8 <sup>+</sup> T Cells and Distal Convoluted Tubules to Promote Salt‐Sensitive Hypertension (2022) DOI

Collaborators

Researchers in the database who share publications

Shengyu Mu University of Arkansas for Medical Sciences 16 shared publications Katherine Deck University of Arkansas for Medical Sciences 15 shared publications Christoph Mora University of Arkansas for Medical Sciences 15 shared publications Yunmeng Liu University of Arkansas for Medical Sciences 3 shared publications Tonya Rafferty University of Arkansas for Medical Sciences 3 shared publications Lin-Xi Li University of Arkansas for Medical Sciences 2 shared publications Lu Huang University of Arkansas for Medical Sciences 2 shared publications J. Tucker Andrews University of Arkansas for Medical Sciences 2 shared publications

Similar Researchers

Based on overlapping research topics

Katherine Deck University of Arkansas for Medical Sciences
Blood Pressure and Hypertension Studies Immune Response and Inflammation Immune Cell Function and Interaction
Strong match 5 shared topics
Shengyu Mu University of Arkansas for Medical Sciences
Blood Pressure and Hypertension Studies Immune Response and Inflammation Immune Cell Function and Interaction
Strong match 5 shared topics
Christoph Mora University of Arkansas for Medical Sciences
Blood Pressure and Hypertension Studies Immune Response and Inflammation Immune Cell Function and Interaction
Good match 4 shared topics
Yunmeng Liu University of Arkansas for Medical Sciences
Immune Response and Inflammation Immune Cell Function and Interaction Cardiovascular Function and Risk Factors
Good match 4 shared topics
Lin-Xi Li University of Arkansas for Medical Sciences
Immune Response and Inflammation Immune Cell Function and Interaction Cardiovascular Function and Risk Factors
Good match 4 shared topics
J. Tucker Andrews University of Arkansas for Medical Sciences
Immune Response and Inflammation Immune Cell Function and Interaction Cardiovascular Function and Risk Factors
Good match 4 shared topics