Dayton M. Petibone Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

National Center for Toxicological Research

faculty

13 h-index 33 pubs 766 cited

Research Areas

Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment Cannabis and Cannabinoid Research Molecular Biology Techniques and Applications Health and Medical Research Impacts

Links

ORCID Research Group

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OverviewAI-generated summary

Dayton M. Petibone's research focuses on evaluating the toxicological effects of various substances, particularly in the context of drug development and risk assessment. Recent publications investigate the in vitro effects of cannabidiol and its metabolites on Sertoli cells, and the mechanistic evaluation of black cohosh extract-induced genotoxicity in human cells. Petibone has also contributed to discussions on the potential value of animal microphysiological systems (MPS) and the 3Rs (Replacement, Reduction, Refinement) in drug development, drawing considerations from the pharmaceutical industry. Further work explores the sufficiency of available data for assessing carcinogenic outcomes following short-term exposure to potentially DNA-reactive drugs.

Petibone's scholarly output includes 33 publications, with a total of 766 citations and an h-index of 13. Key collaborators include Donna L. Mendrick, Volodymyr Tryndyak, Nan Mei, and Mugimane G. Manjanatha, all affiliated with the National Center for Toxicological Research, with whom Petibone has co-authored multiple publications.

Metrics

  • h-index: 13
  • Publications: 33
  • Citations: 766

Selected Publications

  • Assessing carcinogenic outcomes following short-term exposure to potentially DNA-reactive drugs: Are available data sufficient to inform risk assessment? (2025) DOI
  • Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development (2025) DOI
  • Potential value of animal microphysiological systems (2024) DOI
  • In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells (2021) DOI
  • Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells (2021) DOI

Collaborators

Researchers in the database who share publications

Donna L. Mendrick National Center for Toxicological Research 2 shared publications Volodymyr Tryndyak National Center for Toxicological Research 1 shared publication Nan Mei National Center for Toxicological Research 1 shared publication Mugimane G. Manjanatha National Center for Toxicological Research 1 shared publication Sharon D. Shelton National Center for Toxicological Research 1 shared publication Ji‐Eun Seo National Center for Toxicological Research 1 shared publication Frederick A. Beland National Center for Toxicological Research 1 shared publication Linda S. Von Tungeln National Center for Toxicological Research 1 shared publication

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