Donna L. Mendrick Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

National Center for Toxicological Research

faculty

40 h-index 102 pubs 8,958 cited

Research Areas

Pharmacological Effects and Toxicity Studies Drug-Induced Hepatotoxicity and Protection Health Policy Implementation Science Animal Behavior and Welfare Studies Child and Adolescent Health Health and Medical Research Impacts

Links

Research Group

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OverviewAI-generated summary

Donna L. Mendrick's research focuses on advancing toxicological assessments, particularly through the development and implementation of new approach methodologies (NAMs) to reduce reliance on traditional animal models. Her work investigates the use of microphysiological systems, such as liver-chips, for studying drug-induced liver injury and for the broader application of NAMs in drug development.

Mendrick has published on the challenges and considerations for integrating NAMs into nonclinical pharmaceutical assessments from an FDA perspective. She also examines progress made by U.S. federal agencies in adopting alternative testing methods and considers the value of animal microphysiological systems in research and for animal welfare. Her scholarship metrics include an h-index of 40, 102 total publications, and 8,958 total citations, designating her as a highly cited researcher.

Her research group collaborates with colleagues at the National Center for Toxicological Research, including Dayton M. Petibone, Qiang Shi, Ayesha Arefin, and Dustyn A. Barnette. Mendrick's recent publications explore topics such as predictive toxicology for children's health and biology-inspired dynamic microphysiological systems.

Metrics

  • h-index: 40
  • Publications: 102
  • Citations: 8,958

Selected Publications

  • Considerations from the pharmaceutical industry (IQ MPS affiliate) workshop on animal microphysiological systems and 3Rs in drug development (2025) DOI
  • Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare (2025) DOI
  • Potential value of animal microphysiological systems (2024) DOI
  • Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods (2024) DOI
  • Gaps and challenges in nonclinical assessments of pharmaceuticals: An FDA/CDER perspective on considerations for development of new approach methodologies (2023) DOI
  • Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022) DOI

Collaborators

Researchers in the database who share publications

Dayton M. Petibone National Center for Toxicological Research 2 shared publications Qiang Shi National Center for Toxicological Research 1 shared publication Ayesha Arefin National Center for Toxicological Research 1 shared publication Dustyn A. Barnette National Center for Toxicological Research 1 shared publication Katy S Papineau National Center for Toxicological Research 1 shared publication Lijun Ren National Center for Toxicological Research 1 shared publication Laura K. Schnackenberg National Center for Toxicological Research 1 shared publication Paul C. Howard National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Kate Steed University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Drug-Induced Hepatotoxicity and Protection Health and Medical Research Impacts
Good match 3 shared topics
John F. Bowyer National Center for Toxicological Research
Pharmacological Effects and Toxicity Studies Drug-Induced Hepatotoxicity and Protection Health and Medical Research Impacts
Good match 3 shared topics
Amanda L Burrow University of Arkansas for Medical Sciences
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Good match 3 shared topics
Laura James University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Child and Adolescent Health Health and Medical Research Impacts
Good match 3 shared topics
William T Fisher University of Arkansas for Medical Sciences
Pharmacological Effects and Toxicity Studies Child and Adolescent Health Health and Medical Research Impacts
Good match 3 shared topics
Michael Gallagher University of Central Arkansas
Pharmacological Effects and Toxicity Studies Child and Adolescent Health Health and Medical Research Impacts
Good match 3 shared topics