Mahmoud Moradi Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI High Impact

Associate Professor

University of Arkansas at Fayetteville

faculty

21 h-index 174 pubs 1,474 cited

Research Areas

Protein Structure and Dynamics SARS-CoV-2 and COVID-19 Research Computational Drug Discovery Methods Bioinformatics and Genomic Networks Advanced Chemical Physics Studies Microbial infections and disease research Molecular Biology Techniques and Applications Lipid Membrane Structure and Behavior

Links

ORCID Lab Website

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OverviewAI-generated summary

Mahmoud Moradi's research focuses on understanding the physics of biological molecules, particularly proteins and their interactions, using computational methods. He has received federal funding from the National Institutes of Health (NIH) and the National Science Foundation (NSF) for his work. A notable NIH grant of $363,842 supports his investigation into the physics-based characterization of functionally relevant protein conformational dynamics. Additionally, two NSF I-Corps grants, totaling $100,000, were awarded to explore the translation potential of a physics-based computational tool for immunoassay development and for a physics-based binding affinity estimator.

Moradi's recent publications delve into areas such as estimating binding affinity from simulations, characterizing the string method with trajectories, and the mechanisms of transporters. His work also addresses the conformational changes in viral spike proteins, the role of cholesterol in G-protein coupled receptors, and the application of bioorthogonal click labeling for single-molecule imaging of viruses. His scholarship metrics include an h-index of 21, 174 total publications, and 1,474 total citations, designating him as a highly cited researcher.

He actively collaborates with researchers at the University of Arkansas at Fayetteville, including Adithya Polasa, Vivek Govind Kumar, James Losey, and Shadi A. Badiee, with whom he has multiple shared publications. Moradi maintains an active laboratory website to disseminate his research.

Metrics

h-index: 21
Publications: 174
Citations: 1,474

Selected Publications

Molecular Dynamics Simulations of Liposomes: Structure, Dynamics, and Applications (2025) DOI
Comprehensive Insights into the Cholesterol-Mediated Modulation of Membrane Function Through Molecular Dynamics Simulations (2025) DOI
Conformational free energy landscape of a glutamate transporter and microscopic details of its transport mechanism (2025) DOI
Molecular Dynamics Investigation of the Influenza Hemagglutinin Conformational Changes in Acidic pH (2024) DOI
Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling (2024) DOI
Deciphering the Interdomain Coupling in a Gram-Negative Bacterial Membrane Insertase (2024) DOI
Differential Behavior of Conformational Dynamics in Active and Inactive States of Cannabinoid Receptor 1 (2024) DOI
Cholesterol Dependence of the Conformational Changes in Metabotropic Glutamate Receptor 1 (2024) DOI
Investigation of P-glycoprotein transport cycle using molecular dynamics as an approach to reduce anti-cancer drug resistance (2024) DOI
Molecular dynamics simulation analysis of the effects and mechanisms of lipid nanoparticles in drug delivery systems (2024) DOI
The effect of cholesterol concentration on planar and spherical lipid bilayers (2024) DOI
A purely physics-based computational binding affinity estimation from restrained umbrella sampling simulations (2024) DOI
Bioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging (2024) DOI
Addressing the Embeddability Problem in Transition Rate Estimation (2023) DOI
cpSRP43 Is Both Highly Flexible and Stable: Structural Insights Using a Combined Experimental and Computational Approach (2023) DOI