Frederick A. Beland Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Research Chemist
National Center for Toxicological Research
faculty
Research Areas
Links
Is this your profile? Verify and claim your profile
Biography and Research Information
OverviewAI-generated summary
Frederick A. Beland is a Research Chemist at the National Center for Toxicological Research. His work focuses on the toxicological evaluation of chemical substances and their effects on biological systems. Beland has published extensively on topics including carcinogenicity, the effects of specific compounds on cellular development and function, and the toxicity of various compounds in animal models. His research has investigated the impact of substances such as aspartame, methyleugenol, isoeugenol, cannabidiol, and polyethylene glycols.
His research group also explores the molecular mechanisms underlying diet-induced diseases, such as non-alcoholic fatty liver disease, examining alterations in DNA methylation and gene expression in genetically diverse mouse models. Additionally, Beland has contributed to the development and evaluation of alternative methods for dermal absorption studies, utilizing both in vitro models and excised human skin. His work has been recognized with a high h-index of 70 and over 18,000 citations, reflecting a significant body of published research.
Beland collaborates with several colleagues at the National Center for Toxicological Research, including Volodymyr Tryndyak, Igor P. Pogribny, Rose Willett, and Gonçalo Gamboa da Costa, with whom he has co-authored numerous publications. He maintains an active laboratory website and leads a research group, indicating ongoing research activities.
Metrics
- h-index: 70
- Publications: 493
- Citations: 18,882
Selected Publications
- Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits (2025) DOI
- NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite (2025) DOI
- Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice (2025) DOI
- Acetyl L‐Carnitine Protects Zebrafish Embryos From Verapamil and Inorganic Arsenic‐Induced Cardiotoxicity and Developmental Toxicity With No Effect on Supernumerary Motor Neuron Development (2025) DOI
- Flow cytometric analysis of the SARS coronavirus 2 antibodies in human plasma (2025) DOI
- A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice (2024) DOI
- Cellular and molecular alterations in a human hepatocellular in vitro model of nonalcoholic fatty liver disease development and stratification (2023) DOI
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound (2023) DOI
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023) DOI
- Gene expression analyses reveal potential mechanism of inorganic arsenic‐induced apoptosis in zebrafish (2023) DOI
- Polycyclic Aromatic Hydrocarbons, Methylated Polycyclic Aromatic Hydrocarbons, and Polycyclic Azaaromatic Compounds (2023) DOI
- Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro (2023) DOI
- Abstract 6017: Exposure-related DNA methylation and gene expression changes in mammary glands of Sprague Dawley rats treated with lorcaserin (2023) DOI
- Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice (2023) DOI
- Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice (2022) DOI
Collaborators
Researchers in the database who share publications
Similar Researchers
Based on overlapping research topics