Olivia Reyes‐Castro

Researcher

University of Arkansas for Medical Sciences

faculty

3 h-index 43 pubs 32 cited

Research Areas

Bone Metabolism and Diseases Cancer-related molecular mechanisms research Metabolism and Genetic Disorders Genomics and Chromatin Dynamics Molecular Biology Techniques and Applications Health and Medical Research Impacts Diet and metabolism studies

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OverviewAI-generated summary

Olivia Reyes‐Castro's research focuses on the molecular mechanisms underlying skeletal development and maintenance, with a particular emphasis on the role of cellular senescence and metabolism in bone health and disease. Her recent publications investigate the NAD salvage pathway in mesenchymal cells, its essential role in skeletal development in mice, and the identification of senescent osteocytes that contribute to bone destruction in breast cancer metastasis. Reyes‐Castro also explores the impact of estrogen on bone mass through its inhibition of NAD+ metabolism in osteoclasts. Her work utilizes single-cell transcriptomic analysis to understand cellular landscapes in aging bone and disease contexts.

Reyes‐Castro collaborates with several researchers at the University of Arkansas for Medical Sciences, including Aric Anloague, Hayley M. Sabol, Japneet Kaur, and Elena Ambrogini, with whom she shares numerous publications. Her scholarship metrics include an h-index of 3, with 43 total publications and 32 total citations.

Metrics

  • h-index: 3
  • Publications: 43
  • Citations: 32

Selected Publications

  • The Aging Landscape by <scp>scRNAseq</scp> of Mesenchymal Lineage Cells in Mouse Bone (2025) DOI
  • Estrogens protect bone mass by inhibiting NAD <sup>+</sup> metabolism in osteoclasts (2025) DOI
  • Senolytics deplete senescent osteocytes and improve bone health in metastatic breast cancer (2024) DOI
  • Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis (2024) DOI
  • The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice (2023) DOI

Collaborators

Researchers in the database who share publications

Aric Anloague University of Arkansas for Medical Sciences 40 shared publications Hayley M. Sabol University of Arkansas for Medical Sciences 35 shared publications Japneet Kaur University of Arkansas for Medical Sciences 28 shared publications Elena Ambrogini University of Arkansas for Medical Sciences 28 shared publications Charles A. O’Brien University of Arkansas for Medical Sciences 28 shared publications Maria Almeida University of Arkansas for Medical Sciences 24 shared publications Jesús Delgado‐Calle University of Arkansas for Medical Sciences 10 shared publications Intawat Nookaew University of Arkansas for Medical Sciences 3 shared publications

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