Saeed Khan Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Research Microbiologist

National Center for Toxicological Research

faculty

21 h-index 78 pubs 1,362 cited

Research Areas

Genomics and Phylogenetic Studies Antibiotic Resistance in Bacteria Microbial infections and disease research Bacterial Genetics and Biotechnology Molecular Biology Techniques and Applications Microbial Community Ecology and Physiology Bioinformatics and Genomic Networks Salmonella and Campylobacter epidemiology

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ORCID Research Group

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OverviewAI-generated summary

Saeed Khan's research focuses on the microbiological and genomic analysis of various bacterial species, with a particular emphasis on antimicrobial resistance and virulence factors. He investigates the adaptive responses of bacteria to different environments and therapeutic agents, including the impact of antibiotic-impregnated materials on microbial communities like *Pseudomonas aeruginosa*. Khan's work also involves the characterization of clinical isolates, such as *Staphylococcus aureus* from Pakistan and multidrug-resistant *E. coli* from imported shrimp, using comprehensive genomic analyses to identify resistance mechanisms, virulence genes, and mobile genetic elements.

His research group employs a range of molecular biology techniques, including whole-genome sequencing and proteomic analysis, to understand bacterial behavior at a molecular level. Khan has studied the concentration-dependent proteome response of *Staphylococcus epidermidis* biofilms to subinhibitory concentrations of tigecycline. Furthermore, his work extends to developing and comparing methods for detecting bacterial pathogens, such as comparing culture- and PCR-based techniques for *Campylobacter jejuni* detection from fresh produce, and utilizing metagenomic approaches to analyze microbiome composition.

Khan collaborates with several researchers at the National Center for Toxicological Research, including Kidon Sung, Miseon Park, Ohgew Kweon, and Angel Paredes, with whom he has co-authored numerous publications. His scholarly output is marked by a high h-index of 21 and over 1,300 citations across 78 publications, designating him as a highly cited researcher. Khan leads a research group and has recently been active in publishing, with his most recent work appearing in 2025.

Metrics

h-index: 21
Publications: 78
Citations: 1,362

Selected Publications

Quantitative proteomic and phenotypic responses of urinary pathogens to CuO/Cu₂O nanoparticles (2025) DOI
Species-Specific Stress Responses to Selenium Nanoparticles in Pseudomonas aeruginosa and Proteus mirabilis (2025) DOI
Complete genome sequence of cephalosporin and tetracycline-resistant Citrobacter freundii CF51 isolate from a patient with urinary tract infection (2024) DOI
Comprehensive Genomic Analysis of Uropathogenic E. coli: Virulence Factors, Antimicrobial Resistance, and Mobile Genetic Elements (2024) DOI
Phenotypic, genotypic and proteomic variations between poor and robust colonizing Campylobacter jejuni strains (2024) DOI
Chicken Juice Enhances C. jejuni NCTC 11168 Biofilm Formation with Distinct Morphological Features and Altered Protein Expression (2024) DOI
Whole-Genome Sequence Analysis of Antibiotic Resistance, Virulence, and Plasmid Dynamics in Multidrug-Resistant E. coli Isolates from Imported Shrimp (2024) DOI
Unraveling the molecular dynamics of Pseudomonas aeruginosa biofilms at the air–liquid interface (2024) DOI
A Single-Laboratory Performance Evaluation of MALDI-TOF MS in Rapid Identification of Staphylococcus aureus, Cronobacter sakazakii, Vibrio parahaemolyticus, and Some Closely Related Bacterial Species of Public Health Importance (2023) DOI
Draft Genome Sequences of 14 Fluoroquinolone-Resistant Escherichia coli Isolates from Imported Shrimp (2023) DOI
Foodborne Pathogen Biofilms: Development, Detection, Control, and Antimicrobial Resistance (2023) DOI
Concentration-Dependent Global Quantitative Proteome Response of Staphylococcus epidermidis RP62A Biofilms to Subinhibitory Tigecycline (2022) DOI
Draft Genome Sequences of Sixteen Fluoroquinolone-Resistant Extraintestinal Escherichia coli Isolates from Human Patients (2022) DOI
Transcriptomic Response of Human Nosocomial Pathogen Pseudomonas aeruginosa Biofilms Following Continuous Exposure to Antibiotic-Impregnated Catheters (2022) DOI
Draft Genome Sequences of 12 Panton-Valentine Leucocidin-Positive and Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Strains Isolated from an Intensive Care Unit in Pakistan (2022) DOI