A. Edwards
Researcher
University of Arkansas for Medical Sciences
faculty
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Biography and Research Information
OverviewAI-generated summary
A. Edwards' research focuses on understanding mechanisms related to lung development and respiratory health. Recent publications investigate the role of CELA1 in improving alveolar septation in a mouse hyperoxia model, with findings suggesting inhibition of CELA1 can enhance this process. Additional work has involved the development of a novel murine partial tracheal occlusion model designed to study altered respiratory dynamics. Edwards has also explored the function of G-quadruplex DNA in relation to the DEAD-box helicase Ded1p, examining its impact on unwinding activity and liquid–liquid phase separation. This work contributes to the broader field of molecular biology and its application to respiratory disease models.
Metrics
- h-index: 3
- Publications: 16
- Citations: 118
Selected Publications
- Novel murine partial tracheal occlusion model with altered respiratory dynamics (2025) DOI
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development (2025) DOI
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development (2024) DOI
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p (2021) DOI
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