Crystal R. Archer Source Confirmed
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Assistant Professor of Biochemistry
University of Arkansas at Fayetteville
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Biography and Research Information
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Crystal R. Archer, Assistant Professor of Biochemistry at the University of Arkansas, leads a research group investigating the molecular mechanisms of ion channel regulation. Her work focuses on the epithelial sodium channel (ENaC) and potassium voltage-gated channel subfamily T member 1 (Kv7.2), exploring how cellular signaling pathways and protein interactions influence their function.
Recent publications by Archer and her collaborators detail the roles of casein kinase II, ankyrin-3, and NOXA1 in modulating ENaC activity, as well as the impact of P2Y2 receptor signaling on blood pressure via ENaC inhibition. Her group has also employed optogenetic techniques to study the interaction of PIP2 with ENaC and has investigated the potential of TRPM7 channels as therapeutic targets for B cell leukemias. Additionally, Archer has received a $249,000 grant from the NIH/National Institute of General Medical Sciences for research into the structural consequences of PKC-dependent phosphorylation of Kv7.2.
Metrics
- h-index: 8
- Publications: 30
- Citations: 488
Selected Publications
- Abstract 2279 Phosphorylation control of Kv7.2 structure and interactions in response to GPCR signals (2025) DOI
Federal Grants 1 $249,000 total
Structural consequences of PKC-dependent phosphorylation of Kv7.2
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