Dustyn A. Barnette Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Postdoctoral Fellow

National Center for Toxicological Research

postdoc

11 h-index 15 pubs 273 cited

Research Areas

Drug-Induced Hepatotoxicity and Protection Metabolomics and Mass Spectrometry Studies Medical Imaging Techniques and Applications Pharmacological Effects and Toxicity Studies Advanced Neural Network Applications Neuroscience and Neuropharmacology Research Birth, Development, and Health

Links

ORCID Research Group

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OverviewAI-generated summary

Dustyn A. Barnette's research focuses on understanding drug-induced liver injury and identifying biomarkers for toxicity. Barnette has investigated the use of co-cultures of human primary hepatocytes and nonparenchymal liver cells in microphysiological systems to study drug effects. Additionally, Barnette has explored the application of MALDI imaging mass spectrometry as a tool for neurological research and for identifying toxicity markers in preclinical models, such as in utero opioid exposures in mouse fetuses. Machine learning approaches have also been employed to predict drug interactions, specifically concerning non-steroidal anti-inflammatory drugs and liver-injuring medications using electronic health record data. Barnette's work includes identifying novel metabolic pathways for drug compounds, such as the reductive elimination pathway for 10-hydroxywarfarin. Barnette has published 15 papers with 273 citations and an h-index of 11.

Metrics

  • h-index: 11
  • Publications: 15
  • Citations: 273

Selected Publications

  • The incorporation of MALDI mass spectrometry imaging in studies to identify markers of toxicity following in utero opioid exposures in mouse fetuses (2024) DOI
  • Co‐Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver‐Chip for the Study of Drug‐Induced Liver Injury (2022) DOI
  • Discovery of Novel Reductive Elimination Pathway for 10-Hydroxywarfarin (2022) DOI
  • MALDI imaging mass spectrometry: an emerging tool in neurology (2021) DOI
  • Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort (2021) DOI

Collaborators

Researchers in the database who share publications

E. Ellen Jones National Center for Toxicological Research 2 shared publications Laura K. Schnackenberg National Center for Toxicological Research 2 shared publications Grover Miller University of Arkansas for Medical Sciences 2 shared publications David A. Thorn National Center for Toxicological Research 1 shared publication Amy L. Inselman National Center for Toxicological Research 1 shared publication Richard D. Beger National Center for Toxicological Research 1 shared publication Sumit Sarkar National Center for Toxicological Research 1 shared publication Pritpal Malhi National Center for Toxicological Research 1 shared publication

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