Serguei Liachenko Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Director of Bioimaging

National Center for Toxicological Research

faculty

18 h-index 52 pubs 910 cited

Research Areas

Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment Metabolomics and Mass Spectrometry Studies Health and Medical Research Impacts

Links

ORCID Lab Website Research Group

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OverviewAI-generated summary

Serguei Liachenko's research program focuses on the development and application of advanced medical imaging techniques, particularly T2 magnetic resonance imaging (MRI), for the noninvasive assessment of neurotoxicity. His work investigates quantitative biomarkers of brain damage following exposure to various chemical agents. Recent publications detail the use of T2 MRI mapping to detect gadodiamide retention in rat brains and to assess trimethyltin-induced neurotoxicity in rats, with studies exploring its performance at 7 Tesla. Liachenko also investigates the impact of long-term drug administration and withdrawal on neuroimaging markers in animal models, such as methylphenidate in rhesus monkeys. His research contributes to the broader field of regulatory science by exploring emerging technologies for toxicological assessment and has led to the publication of 52 papers, with an h-index of 18 and 910 citations. He collaborates with researchers including Merle G. Paule, William Slikker, Natalya Sadovova, and Sumit Sarkar, all from the National Center for Toxicological Research.

Metrics

  • h-index: 18
  • Publications: 52
  • Citations: 910

Selected Publications

  • Biomarkers of Neurotoxicity and Disease (2025) DOI
  • In vivo mapping of rat brain partial white matter content using hexachlorophene-induced neurotoxicity model (2024) DOI
  • Performance of the prospective T2 MRI biomarker of neurotoxicity in a trimethyltin model in rats at 7 T (2023) DOI
  • The effects of long-term methylphenidate administration and withdrawal on progressive ratio responding and T2 MRI in the male rhesus monkey (2022) DOI
  • Optimization of Detection of Gadodiamide Brain Retention in Rats Using Quantitative <scp>T<sub>2</sub></scp> Mapping and Intraperitoneal Administration (2022) DOI
  • Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity (2021) DOI
  • Global Neurotoxicity: Quantitative Analysis of Rat Brain Toxicity Following Exposure to Trimethyltin (2021) DOI

Collaborators

Researchers in the database who share publications

Merle G. Paule National Center for Toxicological Research 4 shared publications William Slikker National Center for Toxicological Research 3 shared publications Natalya Sadovova National Center for Toxicological Research 3 shared publications Sumit Sarkar National Center for Toxicological Research 3 shared publications Anil K. Patri National Center for Toxicological Research 2 shared publications Weida Tong National Center for Toxicological Research 2 shared publications Richard D. Beger National Center for Toxicological Research 1 shared publication Suman Ghorai National Center for Toxicological Research 1 shared publication

Similar Researchers

Based on overlapping research topics

Arnold Tripp National Center for Toxicological Research
Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Strong match 4 shared topics
Jaivijay Ramu National Center for Toxicological Research
Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Good match 4 shared topics
Suman Ghorai National Center for Toxicological Research
Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Good match 4 shared topics
Bryan Raymick National Center for Toxicological Research
Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Good match 4 shared topics
Susan M. Lantz National Center for Toxicological Research
Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies Carcinogens and Genotoxicity Assessment
Good match 4 shared topics
Natalya Sadovova National Center for Toxicological Research
Medical Imaging Techniques and Applications Neuroscience and Neuropharmacology Research Pharmacological Effects and Toxicity Studies
Good match 4 shared topics