Filipa Ponte

Researcher

University of Arkansas for Medical Sciences

faculty

9 h-index 27 pubs 414 cited

Research Areas

Links

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OverviewAI-generated summary

Filipa Ponte's research focuses on the molecular mechanisms underlying bone loss, particularly in the context of aging and estrogen deficiency. Her work investigates the role of specific cellular components and signaling pathways in maintaining bone mass and structure. Recent publications highlight the contribution of mitochondrial Sirt3 to age-related bone loss and the impact of decreased NAD+ levels on osteoprogenitors. Additionally, her research explores the function of RANK ligand in regulating osteoclast gene expression and the effects of Mmp13 deletion in mesenchymal cells on bone mass and cortical bone loss. Ponte has a h-index of 9, with 27 publications and 414 citations. She has collaborated with researchers at the University of Arkansas for Medical Sciences, including Maria Almeida, Stavros C. Manolagas, Aaron Warren, and Ha‐Neui Kim, with whom she shares multiple publications.

Metrics

h-index: 9
Publications: 27
Citations: 414

Selected Publications

RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression (2023) DOI
Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency (2022) DOI
Mmp13 deletion in mesenchymal cells increases bone mass and attenuates the cortical bone loss caused by estrogen deficiency (2022) DOI
<i>Mmp-13</i> deletion in cells of the mesenchymal lineage increases bone mass, decreases endocortical osteoclast number, and attenuates the cortical bone loss caused by estrogen deficiency in mice (2021) DOI
A decrease in NAD+ contributes to the loss of osteoprogenitors and bone mass with aging (2021) DOI