Ilham Kadhim

Researcher

University of Arkansas for Medical Sciences

unknown

Kadhimilham@uams.edu

3 h-index 5 pubs 14 cited

Research Areas

Bone Metabolism and Diseases Mitochondrial Function and Pathology Autophagy and Lysosomal Biology Molecular Biology Techniques and Applications Cancer-related molecular mechanisms research Aging research

Links

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OverviewAI-generated summary

Ilham Kadhim's research investigates molecular mechanisms influencing bone mass and strength, with a focus on the role of autophagy and mitochondrial function in osteoblast lineage cells. Kadhim has published work examining the impact of the master autophagy regulator Tfeb on bone characteristics, including studies utilizing CRISPR activation to up-regulate Tfeb expression. Further research explores the relationship between mitochondrial oxidative stress, autophagy, and the aging process in bone mechanoresponsiveness. Kadhim has also investigated the encapsulation of inositol hexakisphosphate with chitosan for potential delivery and cell death induction in human breast cancer cells, and the up-regulation of Osh6 in relation to anti-aging membrane trafficking pathways toward vacuoles. Kadhim has a h-index of 3 with 14 citations across 5 publications and collaborates with researchers at the University of Arkansas for Medical Sciences, including Melda Onal, A. Gordon James, and Maria Almeida.

Metrics

  • h-index: 3
  • Publications: 5
  • Citations: 14

Selected Publications

  • Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025) DOI
  • Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness (2025) DOI
  • CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024) DOI
  • Encapsulation of Inositol Hexakisphosphate with Chitosan via Gelation to Facilitate Cellular Delivery and Programmed Cell Death in Human Breast Cancer Cells (2024) DOI

Collaborators

Researchers in the database who share publications

Melda Onal University of Arkansas for Medical Sciences 3 shared publications A. Gordon James University of Arkansas for Medical Sciences 3 shared publications Maria Almeida University of Arkansas for Medical Sciences 3 shared publications Jinhu Xiong University of Arkansas for Medical Sciences 2 shared publications Amy Y. Sato University of Arkansas for Medical Sciences 2 shared publications Julie Crawford University of Arkansas for Medical Sciences 2 shared publications James A. Hendrixson University of Arkansas for Medical Sciences 2 shared publications Jeff Thostenson University of Arkansas for Medical Sciences 2 shared publications

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