John C. Marecki Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Instructor
University of Arkansas for Medical Sciences
faculty
Biochemistry & Molecular Biology, College of Medicine
Research Areas
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Biography and Research Information
OverviewAI-generated summary
John C. Marecki's research centers on molecular mechanisms governing viral replication and RNA processing. His work investigates the role of RNA helicases in viral propagation, examining how these enzymes interact with nucleic acids like G-quadruplex DNA and double-stranded DNA. Marecki's publications explore the structural features of helicases that influence their unwinding activity and their involvement in biomolecular condensates, which play a role in viral replication. He has also contributed to understanding the functional dynamics of viral polymerases, including post-assembly conformational changes that enable elongation. His research network includes collaborators such as Emory G. Malone, Wayne P. Wahls, and Reine U. Protacio from the University of Arkansas for Medical Sciences. Marecki's scholarship metrics include an h-index of 18 and over 1,800 citations across 40 publications.
Metrics
- h-index: 18
- Publications: 40
- Citations: 1,836
Selected Publications
- Biomolecular condensates control and are defined by RNA-RNA interactions that arise in viral replication (2025) DOI
Grants & Funding
- Functions and Mechanisms of Helicases and G-Quadruplex Nucleic Acids NIH Co-Investigator
- Mechanisms of Protection and Pathogenesis in ALS Mice NIH/Nat. Inst. of Neurological Disorders & Stroke Co-Investigator
- Coronavirus Genome Replication Subcontract UNC-CH Craig Cameron NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: University of North Carolina - Chapel Hill Principal Investigator
- Midwest AViDD Center NIH/Nat. Inst. of Allergy & Infectious Diseases - Pass Through: University of Minnesota Principal Investigator
- Center for Molecular Interactions in Cancer (CMIC) NIH Co-Investigator
Collaborators
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