Mason McCrury
Researcher
University of Arkansas for Medical Sciences
faculty
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Biography and Research Information
OverviewAI-generated summary
Mason McCrury's research focuses on understanding the molecular mechanisms underlying cancer, with a particular emphasis on identifying novel therapeutic targets and developing strategies for their inhibition. His work has investigated the role of specific proteins, such as NEK2, in regulating oncogenic pathways in lymphoma. McCrury has also explored the potential of targeting G-quadruplex DNA structures within the promoters of key oncogenes and immune adaptor genes, including CARD11 and MYD88.
His publications demonstrate an interest in DNA synthesis and the disruption of G-quadruplexes by specific molecular motifs, examining their conservation across species. McCrury's research network includes extensive collaborations with colleagues at the University of Arkansas for Medical Sciences, such as Kennith Swafford, Vijay Patel, Ying-Zhi Xu, and Sydnye L. Shuttleworth, with whom he has co-authored numerous publications.
With a career h-index of 3 and over 58 publications, McCrury's work contributes to the broader field of cancer research and therapeutic development. His recent activities indicate ongoing engagement in this area.
Metrics
- h-index: 3
- Publications: 58
- Citations: 24
Selected Publications
- G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025) DOI
- Conservation of the insert-2 motif confers Rev1 from different species with an ability to disrupt G-quadruplexes and stimulate translesion DNA synthesis (2023) DOI
- Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group (2022) DOI
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