Sayed Aliul Hasan Abdi

Researcher

University of Arkansas for Medical Sciences

faculty

11 h-index 43 pubs 413 cited

Research Areas

Cancer-related molecular mechanisms research Computational Drug Discovery Methods Effects and risks of endocrine disrupting chemicals Pharmacological Effects and Toxicity Studies Protein Structure and Dynamics Metabolism and Genetic Disorders Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Sayed Aliul Hasan Abdi's research investigates the molecular mechanisms underlying various health conditions and the potential impacts of environmental exposures. His work includes studies on the molecular basis of oxidative stress in acute kidney injury, exploring the role of compounds like resveratrol. Abdi has also focused on evaluating potential therapeutic candidates for diseases such as prostate cancer, utilizing computational methods like molecular docking and dynamics simulations to screen for inhibitory effects on specific enzymes like CYP17A1. Additionally, his research addresses the endocrine-disrupting potential of common substances, including fungicides and sunscreen ingredients, examining their interactions with hormone-binding globulins and their implications for reproductive health. He also explores adverse drug reactions, such as severe cutaneous adverse reactions to anti-seizure medications.

Metrics

  • h-index: 11
  • Publications: 43
  • Citations: 413

Selected Publications

  • Duloxetine, an SNRI, Targets pSTAT3 Signaling: In-Silico, RNA-Seq and In-Vitro Evidence for a Pleiotropic Mechanism of Pain Relief (2025) DOI
  • Mitochondrial Dynamics in Aging Heart (2025) DOI
  • Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases (2025) DOI
  • The Long-Term Cardiovascular Risks of Duloxetine Use in Older Adults: A Retrospective Medical Record-Based Adverse Drug Reaction Assessment (2024) DOI

Collaborators

Researchers in the database who share publications

Jeanne Y. Wei University of Arkansas for Medical Sciences 4 shared publications Gohar M. Azhar University of Arkansas for Medical Sciences 4 shared publications Mohib Hafeez University of Arkansas for Medical Sciences 1 shared publication Pankaj Patyal University of Arkansas for Medical Sciences 1 shared publication Ambika Verma University of Arkansas for Medical Sciences 1 shared publication Jyotsna Shrivastava University of Arkansas for Medical Sciences 1 shared publication

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