Julie Crawford

Mark van Doren Professor of Humanities

University of Arkansas for Medical Sciences

faculty

12 h-index 54 pubs 754 cited

Research Areas

Bone Metabolism and Diseases Molecular Biology Techniques and Applications Autophagy and Cellular Mechanisms CRISPR and Genetic Engineering Health and Medical Research Impacts Dermatology and Skin Diseases

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OverviewAI-generated summary

Julie Crawford's research focuses on the molecular mechanisms underlying bone metabolism and strength. Her work investigates the role of autophagy, a cellular process responsible for waste removal and recycling, in bone health. Specifically, she has studied the impact of the master autophagy regulator Tfeb on osteoblast lineage cells, finding that its activation can increase bone mass and strength. Crawford has also examined the consequences of chaperone-mediated autophagy loss on bone mass, with findings indicating no alteration in age-related bone loss in male mice. Her publications also include work on comparative cell type specificity of CRISPR interference versus the Cre-loxP system and patient-reported outcomes in atopic dermatitis.

Metrics

  • h-index: 12
  • Publications: 54
  • Citations: 754

Selected Publications

  • Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025) DOI
  • CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024) DOI
  • Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice (2024) DOI
  • CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system (2023) DOI
  • Loss of chaperone-mediated autophagy is associated with low vertebral cancellous bone mass (2022) DOI

Collaborators

Researchers in the database who share publications

Melda Onal University of Arkansas for Medical Sciences 5 shared publications James A. Hendrixson University of Arkansas for Medical Sciences 4 shared publications A. Gordon James University of Arkansas for Medical Sciences 3 shared publications Dominique J. Laster University of Arkansas for Medical Sciences 3 shared publications Nisreen Akel University of Arkansas for Medical Sciences 3 shared publications Stuart B. Berryhill University of Arkansas for Medical Sciences 3 shared publications Intawat Nookaew University of Arkansas for Medical Sciences 2 shared publications Amy Y. Sato University of Arkansas for Medical Sciences 2 shared publications

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