James A. Hendrixson

Researcher

University of Arkansas for Medical Sciences

unknown

3 h-index 4 pubs 15 cited

Research Areas

Bone Metabolism and Diseases CRISPR and Genetic Engineering Autophagy and Cellular Regulation Molecular Biology Techniques and Applications Genomics and Chromatin Dynamics Anatomical Variations Research Medical Education Research and Scholarship

Links

ORCID

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OverviewAI-generated summary

James A. Hendrixson's research focuses on the molecular mechanisms of bone metabolism and the regulation of cellular processes like autophagy. His work has investigated the role of the master autophagy regulator Tfeb in osteoblast lineage cells, finding that its activation can increase bone mass and strength. He has also examined the impact of chaperone-mediated autophagy on age-related bone loss in male mice, indicating that its loss does not alter this process.

Hendrixson has explored advancements in gene editing technologies, comparing the cell type-specificity of CRISPR interference to the Cre-loxP system. His publications demonstrate an interest in the application of molecular biology techniques to understand physiological processes. Hendrixson collaborates with researchers at the University of Arkansas for Medical Sciences, including Melda Onal and Julie Crawford, with whom he has co-authored multiple publications.

Metrics

  • h-index: 3
  • Publications: 4
  • Citations: 15

Selected Publications

  • Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025) DOI
  • CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024) DOI
  • Loss of chaperone‐mediated autophagy does not alter age‐related bone loss in male mice (2024) DOI
  • CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system (2023) DOI
  • Retroaortic Left Renal Vein: An Incidental Finding During Cadaver Dissection (2022) DOI

Collaborators

Researchers in the database who share publications

Melda Onal University of Arkansas for Medical Sciences 4 shared publications Julie Crawford University of Arkansas for Medical Sciences 4 shared publications A. Gordon James University of Arkansas for Medical Sciences 3 shared publications Intawat Nookaew University of Arkansas for Medical Sciences 2 shared publications Amy Y. Sato University of Arkansas for Medical Sciences 2 shared publications Maria Almeida University of Arkansas for Medical Sciences 2 shared publications Ilham Kadhim University of Arkansas for Medical Sciences 2 shared publications Jeff Thostenson University of Arkansas for Medical Sciences 2 shared publications

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