Shilpi Agrawal Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Researcher

University of Arkansas at Little Rock

faculty

10 h-index 55 pubs 471 cited

Research Areas

Protein Structure and Dynamics CRISPR and Genetic Engineering Molecular Biology Techniques and Applications Bioinformatics and Genomic Networks SARS-CoV-2 and COVID-19 Research Computational Drug Discovery Methods

Links

ORCID

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OverviewAI-generated summary

Shilpi Agrawal's research investigates the structural and mechanistic aspects of protein dynamics, with a particular focus on fibroblast growth factors and their interactions with heparin. Her work has involved computational simulations, such as restrained umbrella sampling, to estimate binding affinities and characterize the forces governing protein stability and unfolding reversibility. Agrawal has also explored advancements in CRISPR-based technologies, including their application in diagnosing and treating diseases like COVID-19 and Duchenne muscular dystrophy, as well as optimizing protein expression for genome editing applications. Her collaborations include extensive work with Christopher E. Nelson at the University of Arkansas at Little Rock, Thallapuranam Krishnaswamy Suresh Kumar and Mahmoud Moradi at the University of Arkansas System, and Made Harumi Padmaswari at the University of Arkansas at Little Rock. Agrawal's scholarly output includes 55 publications, with 471 citations and an h-index of 10.

Metrics

  • h-index: 10
  • Publications: 55
  • Citations: 471

Selected Publications

  • Beyond the Cut: Long-read sequencing reveals complex genomic and transcriptomic changes in AAV-CRISPR therapy for Duchenne Muscular Dystrophy (2025) DOI
  • Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education (2025) DOI
  • Unraveling Attention-Deficit/Hyperactivity Disorder Etiology: Current Challenges and Future Directions in Treatment (2025) DOI
  • Preclinical development of genome editing to treat Duchenne muscular dystrophy by exon skipping (2025) DOI
  • Structural Stability Comparisons Between Natural and Engineered Group II Chaperonins: Are Crenarchaeal “Heat Shock” Proteins Also “pH Shock” Resistant? (2024) DOI
  • Advancing CRISPR-Based Solutions for COVID-19 Diagnosis and Therapeutics (2024) DOI
  • Resistance to Acetyl Coenzyme A Carboxylase (ACCase) Inhibitor in Lolium multiflorum: Effect of Multiple Target-Site Mutations (2024) DOI
  • Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024) DOI
  • Optimizing Recombinant Cas9 Expression: Insights from E. coli BL21(DE3) Strains for Enhanced Protein Purification and Genome Editing (2024) DOI
  • Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci (2024) DOI
  • CRISPR-Cas9 Unleashed: Gene-Slicing Adventures in the Cancer Battlefield (2024) DOI
  • Delivery challenges for CRISPR—Cas9 genome editing for Duchenne muscular dystrophy (2023) DOI
  • Overexpression and cell-penetrating peptide-mediated delivery of Cas9 and its variant(s) for targeted genome editing (2023) DOI
  • Binding affinity estimation from restrained umbrella sampling simulations (2022) DOI
  • Binding Affinity Estimation from Restrained Umbrella Sampling Simulations (2022) DOI

Collaborators

Researchers in the database who share publications

Christopher E. Nelson University of Arkansas at Little Rock 10 shared publications Thallapuranam Krishnaswamy Suresh Kumar University of Arkansas at Fayetteville 8 shared publications Made Harumi Padmaswari University of Arkansas at Little Rock 6 shared publications Mahmoud Moradi University of Arkansas at Fayetteville 5 shared publications Vivek Govind Kumar University of Arkansas at Fayetteville 5 shared publications Abbey L. Stokes University of Arkansas at Little Rock 4 shared publications Zeina Alraawi University of Arkansas at Fayetteville 4 shared publications Shivakumar Sonnaila University of Arkansas at Fayetteville 4 shared publications

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