Behjatolah Monzavi Karbassi profile photo

Behjatolah Monzavi Karbassi Institution Verified

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Federal Grant PI

Associate Professor

University of Arkansas for Medical Sciences

faculty

Pathology, College of Medicine

6 pubs

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Biography and Research Information

OverviewAI-generated summary

Behjatolah Monzavi Karbassi's research focuses on the molecular mechanisms underlying disease, particularly within the context of the immune system and cancer. His work investigates the role of specific molecules, such as CST6, in modulating the microenvironment of conditions like multiple myeloma, with implications for immunosuppression. He also explores strategies for cancer immunotherapy, including the potential of antibody polyspecificity. Monzavi Karbassi has published a total of six scholarly works and has secured federal grant funding as a principal investigator. He collaborates with researchers at the University of Arkansas for Medical Sciences, including Brian Koss and David E. Mery, on shared publications.

Metrics

  • Publications: 6

Selected Publications

  • The Role of CST6 in Immunosuppression in the Multiple Myeloma Microenvironment (2024) DOI

Research Interests

My primary research interest is in developing immunotherapeutic strategies to potentiate the anti-cancer immune response by targeting immune suppression within the tumor microenvironment. Central to my approach is the investigation of tumor-associated glycans (TAGs) as therapeutic targets, with a particular emphasis on breast cancer.

Grants & Funding

  • Mimotope Conversion of HIV-1 Carbohydrate Antigens NIH Co-Investigator
  • Vaccination of High-Risk Breast Cancer patients with Carbohydrate Mimicking Peptides US Department of the Army Co-Investigator
  • Ex vivo models of breast cancer for the development of novel drug combinations, a pilot study. Arkansas Breast Cancer Research Program Co-Investigator
  • Role of scavenger receptor-A (SR-A) binding to tumor-associated glycans Arkansas Breast cancer Research program Co-Investigator
  • SR-A as a therapeutic target in breast cancer NIH/Nat. Cancer Institute Co-Principal Investigator
  • Defining Tumor-Associated Glycans on Breast Cancer Cells that are Ligands for Macrophage SR-A UAMS Medical Research Endowment fund Principle Investigator
  • SR-A as a therapeutic target in breast cancer NIH Co-Principal Investigator
  • Explant models and derived primary cell lines for the discovery and testing of novel therapies for breast cancer. Arkansas Breast Cancer Research Program. Co-Investigator

Collaborators

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