Gohar M. Azhar Institution Verified

Sourced from institutional research profiles (UAMS TRI or ARA).

High Impact

Researcher

University of Arkansas for Medical Sciences

faculty

32 h-index 525 pubs 3,032 cited

Research Areas

Mitochondrial Function and Pathology Neuroinflammation and Neurodegeneration Mechanisms Diet and metabolism studies Microbial infections and disease research Pharmacological Effects and Toxicity Studies Molecular Biology Techniques and Applications Health and Medical Research Impacts

Links

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OverviewAI-generated summary

Gohar M. Azhar's research focuses on the molecular mechanisms underlying mitochondrial dysfunction, neuroinflammation, and oxidative stress. Recent publications investigate the role of specific amino acids, such as valine, in improving mitochondrial function and protecting against cellular damage. Azhar's work also examines the impact of bacterial lipopolysaccharides, specifically from Porphyromonas gingivalis, on inducing mitochondrial dysfunction and neuroinflammation in cellular models. This research contributes to understanding the pathways involved in neurodegenerative processes and potential therapeutic interventions.

Further investigations by Azhar explore the effects of dietary interventions and supplements on physical performance, particularly in older adults. Studies have also analyzed the impact of specific inhibitors on mitochondrial functions and investigated alternative splicing in gene families like Sirtuins, which are involved in cellular regulation and metabolism. Azhar leads a research group and has a significant publication record, evidenced by an h-index of 32 and over 500 publications, collaborating with multiple colleagues at the University of Arkansas for Medical Sciences.

Metrics

  • h-index: 32
  • Publications: 525
  • Citations: 3,032

Selected Publications

  • Biology of Aging I Antisense Oligonucleotide-Mediated SRF Reduction Ameliorates Mitochondrial Dysfunction in Cardiac Aging (2025) DOI
  • Dysregulation of SRF-Regulated Genes Accelerates the Development of Myocardial Aging (2025) DOI
  • Assessment of Caregiver Stress Across Dementia and Non-Dementia Groups (2025) DOI
  • Isoform-specific roles of SIRT2 in regulating mitochondrial gene expression (2025) DOI
  • P. gingivalis-LPS Activates the Alzheimer’s Disease-Associated Amyloid Secretase Pathway via Caspase-4 (2025) DOI
  • Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas (2025) DOI
  • Duloxetine, an SNRI, Targets pSTAT3 Signaling: In-Silico, RNA-Seq and In-Vitro Evidence for a Pleiotropic Mechanism of Pain Relief (2025) DOI
  • Mitochondrial Dynamics in Aging Heart (2025) DOI
  • Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases (2025) DOI
  • Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025) DOI
  • Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease Pathologies (2025) DOI
  • DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024) DOI
  • P. GINGIVALIS-LPS PROMOTES AD/ADRD VIA CASPASE-4-MEDIATED NONCANONICAL INFLAMMASOME PATHWAY (2024) DOI
  • Effect of 3 Different Daily Protein Intakes in a 2-Meal Eating Pattern on Protein Turnover in Middle Age and Older Adults: A Randomized Controlled Trial (2024) DOI
  • The Long-Term Cardiovascular Risks of Duloxetine Use in Older Adults: A Retrospective Medical Record-Based Adverse Drug Reaction Assessment (2024) DOI

Grants & Funding

Collaborators

Researchers in the database who share publications

Jeanne Y. Wei University of Arkansas for Medical Sciences 37 shared publications Pankaj Patyal University of Arkansas for Medical Sciences 21 shared publications Ambika Verma University of Arkansas for Medical Sciences 20 shared publications Amanda Pangle University of Arkansas for Medical Sciences 12 shared publications Robert R. Wolfe University of Arkansas for Medical Sciences 6 shared publications Gohar M. Azhar University of Arkansas for Medical Sciences 6 shared publications Karen Coker University of Arkansas for Medical Sciences 6 shared publications Sayed Aliul Hasan Abdi University of Arkansas for Medical Sciences 4 shared publications

Similar Researchers

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Bachkhoa Nguyen University of Arkansas for Medical Sciences
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Yingni Che University of Arkansas for Medical Sciences
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Ambika Verma University of Arkansas for Medical Sciences
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Joanna Fiddler University of Arkansas at Fayetteville
Mitochondrial Function and Pathology Diet and metabolism studies Pharmacological Effects and Toxicity Studies
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